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Hepatic Encephalopathy (CTRC) (Size: 3.46 MB)
DescriptionBecause of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy. Table of contents : Front Matter....Pages i-xiii Introduction, Nomenclature, and Classification of Hepatic Encephalopathy....Pages 1-4 Front Matter....Pages 5-5 Role of Ammonia in the Pathogenesis of Hepatic Encephalopathy....Pages 7-17 Neuroinflammation in the Pathogenesis of Hepatic Encephalopathy....Pages 19-34 Inflammation and Hepatic Encephalopathy....Pages 35-45 Oxidative Stress in Hepatic Encephalopathy....Pages 47-70 The Role of Natural Benzodiazepines Receptor Ligands in Hepatic Encephalopathy....Pages 71-93 Front Matter....Pages 95-95 Diagnosis of Overt Hepatic Encephalopathy....Pages 97-102 Diagnosis of Minimal Hepatic Encephalopathy....Pages 103-112 The Electroencephalogram in Hepatic Encephalopathy....Pages 113-121 Brain Imaging in Hepatic Encephalopathy....Pages 123-137 Front Matter....Pages 139-139 Disaccharides in the Treatment of Hepatic Encephalopathy....Pages 141-158 Antibiotic Treatment for Hepatic Encephalopathy....Pages 159-164 Ornithine Phenylacetate: A Novel Strategy for the Treatment of Hepatic Encephalopathy....Pages 165-174 Front Matter....Pages 175-175 Sleep Disorders and Hepatic Encephalopathy....Pages 177-186 Hepatic Encephalopathy and Driving....Pages 187-197 Nutrition and Hepatic Encephalopathy....Pages 199-209 Hepatic Encephalopathy in Patients with Transjugular Intrahepatic Portosystemic Shunt (TIPS)....Pages 211-220 Quality of Life in Hepatic Encephalopathy....Pages 221-231 Liver Transplantation and Hepatic Encephalopathy....Pages 233-239 Future of Hepatic Encephalopathy....Pages 241-243 Back Matter....Pages 245-250 Sharing Widget |
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