Encyclopedia of Pharmaceutical Manufacturing

Encyclopedia of Pharmaceutical Manufacturing
Author: Marshall Sittig
Publisher: NOYES PUBLICATIONS

This encyclopedic work gives details for the manufacture of 1295 pharmaceuticals, now
being marketed as trade-named products somewhere in the world. The pertinent process
information has been obtained from examples given in the pertinent patent literature
(usually U.S. patents and sometimes British patents).
In addition to the patent-derived process information, references are also cited under each
drug's entry to major pharmaceutical reference works where additional information can be
obtained on synthesis methods and the pharmacology of the individual products.
This work is presented in two volumes. The arrangement within the books is alphabetic by
generic name. The table of contents appears at the beginning of Volume 1. There is also an
index by trade names used in many of the countries in the world. Another index lists the
raw materials used in the manufacture of the various drugs, an index which should be commercially
valuable to suppliers of chemical raw materials to the pharmaceutical industry.
These indexes appear at the end of Volume 2.
These volumes provide a handy first reference both to manufacturing process and also to
other reference sources where additional details on the product may be found.
This handbook should be useful as an initial point of access to the commercial pharmaceutical
literature. It can be consulted as a master source before using computerized retrieval
even if computer data on the pertinent literature are readily available.
This work summarizes practical information available from the work of hundreds of pharmaceutical
research laboratories and of thousands of chemists in those laboratories in developing
thousands of commercial products.
Finally, it is hoped that these books will offer a sort of blueprint for entry into profitable
generic drug manufacture. Companies not now in the drug business but with some expertise
in fermentation processes and/or chemical synthesis may be able to add a few technical people
and make a relatively small investment to get themselves on the first rung of the ladder to
being pharmaceutical producers. Study of available technology, patent expiration dates and
existing markets for particular trade-named drugs may well lead to routes to promising new
ventures.